Based on 4 a daily weather data and traffic accidents statistical data of last 10 a, which is from traffic management departments, the analysis on major meteorological factors with respect to transportation safety on highway is conducted. The results showed that the meteorological factors vary distinctly between different highway sections, which displayed as follows:(1) rainy days in nighttime are about 30 d more than that in daytime; (2) in Zhensheng highway section the maximum rain, heavy rain and rainstorm are the most frequent; (3) the weakest visibility occurs in Yukai highway section, and secondly in Guixin and Zhensheng;(4) congealment occurs most frequently in Zhensheng, Guihuang and Guixin highway section, and snow falls most frequently in Congzun highway section；(5) Yukai highway section has the maximum high-temperature weather days. In addition, a method of forecasting traffic meteorological index is discussed according to weather conditions including rainfall, visibility, congealment and high-temperature. Results of the forecasting are provided for internet services and they are helpful to drivers.